

| Numéro de catalogue | HB816013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human MIF Recombinant Antibody (SAA2333) (HB816013) is a mouse monoclonal antibody detecting MIF in ELISA, Blocking. Suitable for Human, Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||
| Applications | ELISA, Blocking | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| ID de clone | SAA2333 | ||||
| Cible | Macrophage migration inhibitory factor, MIF, EC:5.3.2.1, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, EC:5.3.3.12, Phenylpyruvate tautomerase, MIF, GLIF, MMIF | ||||
| Niveau d'endotoxines | < 10 EU/mg as determined by LAL method. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P14174, P34884 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Macrophage migration inhibitory factor (MIF) is a ~12 kDa protein. Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. 1. Oddo, M. et al. (2005) Infection and immunity 73, 3783-6. PMID: 15908412 2. Emonts, M. et al. (2007) Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 44, 1321-8. PMID: 17443469 3. Fan, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10994-9. PMID: 23776208 4. Tan, TH. et al. (2001) The Biochemical journal 357, 373-83. PMID: 11439086 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human MIF Antibody (SAA2333)
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