

| Numéro de catalogue | HW599014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MNAT1 Polyclonal Antibody (HW599014) is a rabbit polyclonal antibody detecting MNAT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MNAT1 (Met1-Lys130). | ||||||||
| Cible | p36, MNAT1, MAT1, Menage a trois, Cyclin-G1-interacting protein, RING finger protein MAT1, RING finger protein 66, RNF66, CDK7/cyclin-H assembly factor, p35, CAP35, CDK-activating kinase assembly factor MAT1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P51948 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | CDK-activating kinase assembly factor MAT1 (MNAT1) is a ~35 kDa protein. Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-DYNLT1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: A549 cell lysate
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