

| Каталожный номер | HW599014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human MNAT1 Polyclonal Antibody (HW599014) is a rabbit polyclonal antibody detecting MNAT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human MNAT1 (Met1-Lys130). | ||||||||
| Цель | p36, MNAT1, MAT1, Menage a trois, Cyclin-G1-interacting protein, RING finger protein MAT1, RING finger protein 66, RNF66, CDK7/cyclin-H assembly factor, p35, CAP35, CDK-activating kinase assembly factor MAT1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P51948 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | CDK-activating kinase assembly factor MAT1 (MNAT1) is a ~35 kDa protein. Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-DYNLT1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: A549 cell lysate
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