Anti-Human/Mouse CCR1 Recombinant Antibody (SAA2407) (HB896023)

Name: Anti-Human/Mouse CCR1 Recombinant Antibody (SAA2407)
Brand: abinScience
SKU: HB896023
Price: 191 USD
Availability: InStock

データシート製品共有情報コピー

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50ug
100ug
1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HB896023

種反応性

Human, Mouse

アプリケーション

ELISA, FCM, Neutralization

宿主種

Mouse

クローン性

Monoclonal

アイソタイプ

IgG2a, kappa

クローンID

SAA2407

ターゲット

C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, RANTES-R, CD191, CCR1, CMKBR1, CMKR1, SCYAR1

エンドトキシンレベル

< 10 EU/mg

純度

>95% as determined by SDS-PAGE.

精製

Protein A/G purified from cell culture supernatant.

アクセッション番号

P32246, P51675

形態

Liquid

保存バッファー

0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:2000-1:20000

背景

C-C chemokine receptor type 1 (CD191/CCR1) is a ~41 kDa protein. Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses. Contributes to the inflammatory response by recruiting immune cells, such as monocytes, macrophages, T-cells, and dendritic cells, to sites of inflammation for the clearance of pathogens and the resolution of tissue damage. When activated by its ligands including CCL3, CCL5-9, CCL13-16 and CCL23, triggers a signaling cascade within immune cells, leading to their migration towards the source of the chemokine. For example, mediates neutrophil migration after activation by CCL3 leading to the sequential release of TNF and leukotriene B4. Also mediates monocyte migration upon CXCL4 binding.

1. Tian, Y. et al. (2004) European journal of immunology 34, 785-795. PMID: 14991608

2. Berahovich, RD. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 7341-51. PMID: 15905581

3. Wei, H. et al. (2024) Cellular signalling 117, 111122. PMID: 38417634

4. Fox, JM. et al. (2018) Scientific reports 8, 9466. PMID: 29930254

注意事項

For research use only

イメージ

SDS-PAGE

SDS-PAGE for Anti-Human/Mouse CD191/CCR1 Antibody (SAA2407)

参考文献

データシート

Anti-Human/Mouse CCR1 Recombinant Antibody (SAA2407).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human/Mouse CCR1 Recombinant Antibody (SAA2407) (HB896023)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ