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| カタログ番号 | HY280033 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||
| アプリケーション | ELISA, FACS, Functional assay, Research in vivo | ||||
| 宿主種 | Armenian hamster | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG | ||||
| クローンID | 2H5 | ||||
| ターゲット | C-C motif chemokine 2, CCL2, HC11, MCAF, MCP-1, MCP1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2 | ||||
| エンドトキシンレベル | <1 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 関連製品 | pH 7.4 Dilution Buffer | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P13500, P10148, P14844 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | C-C motif chemokine 2 (CCL2/MCP-1) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. 1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171 2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439 3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883 4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247 5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182 6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674 7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690 | ||||
| 注意事項 | For research use only |
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