Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R) (HB186013)

Name: Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R)
Brand: abinScience
SKU: HB186013
Price: 110 USD
Availability: InStock

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1mg

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Aperçu

Numéro de catalogue

HB186013

Description

Anti-Human/Mouse/Rat KCNA4 Recombinant Antibody (K13/31R) (HB186013) is a mouse monoclonal antibody detecting KCNA4/Kv1.4 K+ channel in IHC, IP, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

IHC, IP, WB

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

K13/31R

Cible

Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, HPCN2, Voltage-gated K(+) channel HuKII, Potassium voltage-gated channel subfamily A member 4, KCNA4L, KCNA4, Voltage-gated potassium channel subunit Kv1.4

Niveau d'endotoxines

< 10 EU/mg as determined by LAL method.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P22459

RRID

Anti-Human/Mouse/Rat KCNA4 Antibody (K13/31R) (abinScience Cat# HB186013, RRID:AB_3727195)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Potassium voltage-gated channel subfamily A member 4 (KCNA4/Kv1.4 K+ channel) is a ~73 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.

1. Ramaswami, M. et al. (1990) Molecular and cellular neurosciences 1, 214-23. PMID: 19912772

2. Po, S. et al. (1993) Circulation research 72, 1326-36. PMID: 8495559

3. Imbrici, P. et al. (2006) The European journal of neuroscience 24, 3073-83. PMID: 17156368

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human/Mouse/Rat KCNA4 Antibody (K13/31R)

Reférences

Fiche technique

Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R) (HB186013)

Aperçu

Images

Reférences

Fiche technique

SDS