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Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R) (HB186013)

Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R)
Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R)
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Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
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Обзор
Каталожный номерHB186013
Описание
Anti-Human/Mouse/Rat KCNA4 Recombinant Antibody (K13/31R) (HB186013) is a mouse monoclonal antibody detecting KCNA4/Kv1.4 K+ channel in IHC, IP, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Реактивность видовHuman, Mouse, Rat
ПримененияIHC, IP, WB
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG2a, kappa
ID клонаK13/31R
Цель Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, HPCN2, Voltage-gated K(+) channel HuKII, Potassium voltage-gated channel subfamily A member 4, KCNA4L, KCNA4, Voltage-gated potassium channel subunit Kv1.4
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P22459
RRID Anti-Human/Mouse/Rat KCNA4 Antibody (K13/31R) (abinScience Cat# HB186013, RRID:AB_3727195)
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

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Информация об использовании продукта
Применение Разбавление
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Potassium voltage-gated channel subfamily A member 4 (KCNA4/Kv1.4 K+ channel) is a ~73 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.

1. Ramaswami, M. et al. (1990) Molecular and cellular neurosciences 1, 214-23. PMID: 19912772
2. Po, S. et al. (1993) Circulation research 72, 1326-36. PMID: 8495559
3. Imbrici, P. et al. (2006) The European journal of neuroscience 24, 3073-83. PMID: 17156368
Примечание For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Изображения
  • Anti-Human/Mouse/Rat KCNA4/Kv1.4 Recombinant Antibody (K13/31R)

    SDS-PAGE

    SDS-PAGE for Anti-Human/Mouse/Rat KCNA4 Antibody (K13/31R)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
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Formula
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Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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