

| Каталожный номер | HT215014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human MPHOSPH10 Polyclonal Antibody (HT215014) is a rabbit polyclonal antibody detecting MPHOSPH10 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human MPHOSPH10 (Asp461-Leu681). | ||||||||
| Цель | U3 small nucleolar ribonucleoprotein protein MPP10, M phase phosphoprotein 10, MPHOSPH10, MPP10 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O00566 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | U3 small nucleolar ribonucleoprotein protein MPP10 (MPHOSPH10) is a ~78 kDa protein. Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. 1. Granneman, S. et al. (2003) Nucleic acids research 31, 1877-87. PMID: 12655004 2. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-MPHOSPH10 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
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