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| カタログ番号 | HC456014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human MRPL58 Polyclonal Antibody (HC456014) is a rabbit polyclonal antibody detecting MRPL58 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MRPL58 (Asp71-Asp206). | ||||||||
| ターゲット | DS1, MRPL58, Immature colon carcinoma transcript 1 protein, Digestion substraction 1, Mitochondrial large ribosomal subunit protein mL62, DS-1, ICT1, MRP-L58, Peptidyl-tRNA hydrolase ICT1, mitochondrial, 39S ribosomal protein L58, mitochondrial | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q14197 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Large ribosomal subunit protein mL62 (MRPL58) is a ~23 kDa protein. Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. Involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. 1. Richter, R. et al. (2010) The EMBO journal 29, 1116-25. PMID: 20186120 2. Kummer, E. et al. (2021) Molecular cell 81, 2566-2582.e6. PMID: 33878294 | ||||||||
| 注意事項 | For research use only. |
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