

| Número de catálogo | HA093014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human MTA3 Polyclonal Antibody (HA093014) is a rabbit polyclonal antibody detecting MTA3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human MTA3 (Met1-Lys147). | ||||||||
| Objetivo | Metastasis-associated protein MTA3, MTA3, KIAA1266 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9BTC8 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Metastasis-associated protein MTA3 is a ~67 kDa protein. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. 1. Fujita, N. et al. (2003) Cell 113, 207-19. PMID: 12705869 2. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440 3. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666 4. Fujita, N. et al. (2004) Cell 119, 75-86. PMID: 15454082 | ||||||||
| Nota | For research use only. |
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