

| Número de catálogo | HB492014 | ||||||||
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| Descripción |
Anti-Human MTO1 Polyclonal Antibody (HB492014) is a rabbit polyclonal antibody detecting Protein MTO1 homolog in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human MTO1 (Ala518-Thr675). | ||||||||
| Objetivo | Protein MTO1 homolog, mitochondrial; MTO1; CGI-02 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9Y2Z2 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial is a ~79 kDa protein. Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity. 1. Asano, K. et al. (2018) Nucleic acids research 46, 1565-1583. PMID: 29390138 2. Peng, GX. et al. (2021) Nucleic acids research 49, 2816-2834. PMID: 33619562 | ||||||||
| Nota | For research use only |
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