

| Numéro de catalogue | HC460014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human MXD1 Polyclonal Antibody (HC460014) is a rabbit polyclonal antibody detecting MXD1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MXD1 (Met1-Ser145). | ||||||||
| Cible | Protein MAD, MXD1, MAD, Max dimerizer 1, Max dimerization protein 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q05195 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Max dimerization protein 1 (MXD1) is a ~25 kDa protein. Component of a transcriptional repressor complex together with MAX. In complex with MAX binds to the core DNA sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing with MYC for MAX binding. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding. 1. Ayer, DE. et al. (1993) Cell 72, 211-22. PMID: 8425218 2. Lin, SY. et al. (2003) Cell 113, 881-9. PMID: 12837246 | ||||||||
| Note | For research use only. |
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