

| Numéro de catalogue | HC499014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MYO9B (Pro1691-Ala1916). | ||||||||
| Cible | MYO9B, Unconventional myosin-IXb, MYR5, Unconventional myosin-9b | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q13459 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Unconventional myosin-IXb (MYO9B) is a ~243 kDa protein. Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activator for RHOA. Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. 1. Post, PL. et al. (1998) Journal of cell science 111 ( Pt 7), 941-50. PMID: 9490638 2. Kong, R. et al. (2015) The Journal of clinical investigation 125, 4407-20. PMID: 26529257 | ||||||||
| Note | For research use only. |
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