Anti-Human NASP Polyclonal Antibody (HC209014)

Name: Anti-Human NASP Polyclonal Antibody
Brand: abinScience
SKU: HC209014
Price: 168 USD
Availability: InStock

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Prix(USD) : --

Spécification :

50ug
100ug

Nombre :

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Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC209014

Description

Anti-Human NASP Polyclonal Antibody (HC209014) is a rabbit polyclonal antibody detecting NASP. Suitable for Mouse, Human, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human NASP (Gly513-Gly681).

Cible

NASP, Nuclear autoantigenic sperm protein

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P49321

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Nuclear autoantigenic sperm protein (NASP) is a ~85 kDa protein. Component of the histone chaperone network. Binds and stabilizes histone H3-H4 not bound to chromatin to maintain a soluble reservoir and modulate degradation by chaperone-mediated autophagy. Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.

1. Cook, AJ. et al. (2011) Molecular cell 44, 918-27. PMID: 22195965

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-NASP polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: 293T cell lysate
Lane 3: HL-60 cell lysate

Reférences

Fiche technique

Anti-Human NASP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human NASP Polyclonal Antibody (HC209014)

Aperçu

Images

Reférences

Fiche technique

SDS