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Anti-Human NAXE Polyclonal Antibody (HV343014)

Anti-Human NAXE Polyclonal Antibody
Anti-Human NAXE Polyclonal Antibody
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Aperçu
Numéro de catalogueHV343014
Description
Anti-Human NAXE Polyclonal Antibody (HV343014) is a rabbit polyclonal antibody detecting NAXE in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, Sus scrofa, and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human NAXE (Gly118-Glu282).
Cible NAXE
Purification Purified by antigen affinity column.
Numéro d'accès Q8NCW5
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsNAD(P)H-hydrate epimerase, 5.1.99.6, Apolipoprotein A-I-binding protein, AI-BP, NAD(P)HX epimerase, YjeF N-terminal domain-containing protein 1, YjeF_N1, NAXE, AIBP, APOA1BP, YJEFN1
Contexte

NAD(P)H-hydrate epimerase (NAXE) is a ~31 kDa protein. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.

1. Kremer, LS. et al. (2016) American journal of human genetics 99, 894-902. PMID: 27616477
2. Fang, L. et al. (2013) Nature 498, 118-22. PMID: 23719382
Note For research use only.
Images
  • Anti-Human NAXE Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-NAXE polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse kidney lysate
    Lane 2: Rat liver lysate
    Lane 3: Rat kidney lysate
    Lane 4: Rat heart lysate
    Lane 5: Rat testis lysate

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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