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| カタログ番号 | HV343014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human NAXE Polyclonal Antibody (HV343014) is a rabbit polyclonal antibody detecting NAXE in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, Human, Sus scrofa, and Bovine.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NAXE (Gly118-Glu282). | ||||||||
| ターゲット | NAXE | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8NCW5 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | NAD(P)H-hydrate epimerase, 5.1.99.6, Apolipoprotein A-I-binding protein, AI-BP, NAD(P)HX epimerase, YjeF N-terminal domain-containing protein 1, YjeF_N1, NAXE, AIBP, APOA1BP, YJEFN1 | ||||||||
| 背景 | NAD(P)H-hydrate epimerase (NAXE) is a ~31 kDa protein. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. 1. Kremer, LS. et al. (2016) American journal of human genetics 99, 894-902. PMID: 27616477 2. Fang, L. et al. (2013) Nature 498, 118-22. PMID: 23719382 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-NAXE polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse kidney lysate
Lane 2: Rat liver lysate
Lane 3: Rat kidney lysate
Lane 4: Rat heart lysate
Lane 5: Rat testis lysate
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