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| カタログ番号 | HD230014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human NCAPD2 Polyclonal Antibody (HD230014) is a rabbit polyclonal antibody detecting NCAPD2. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NCAPD2 (Met1-Thr400). | ||||||||
| ターゲット | CAPD2, CNAP1, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, Condensin complex subunit 1, KIAA0159, NCAPD2, Non-SMC condensin I complex subunit D2, XCAP-D2 homolog, hCAP-D2 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q15021 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Condensin complex subunit 1 (NCAPD2) is a ~157 kDa protein. Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. 1. Kimura, K. et al. (2001) The Journal of biological chemistry 276, 5417-20. PMID: 11136719 2. Martin, CA. et al. (2016) Genes & development 30, 2158-2172. PMID: 27737959 | ||||||||
| 注意事項 | For research use only |
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