

| Каталожный номер | HD614014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human NCBP3 Polyclonal Antibody (HD614014) is a rabbit polyclonal antibody detecting NCBP3. Suitable for Mouse and Human.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human NCBP3 (Asp79-Ile294). | ||||||||
| Цель | C17orf85, NCBP3, Nuclear cap-binding protein subunit 3, Protein ELG | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q53F19 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Фон | Nuclear cap-binding protein subunit 3 (NCBP3) is a ~70 kDa protein. Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth. 1. Gebhardt, A. et al. (2015) Nature communications 6, 8192. PMID: 26382858 | ||||||||
| Примечание | For research use only |
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