

| Número de catálogo | HP376014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human NDUFA13 Polyclonal Antibody (HP376014) is a rabbit polyclonal antibody detecting NDUFA13 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human NDUFA13 (Met51-Thr144). | ||||||||
| Objetivo | Gene associated with retinoic and IFN-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, CI-B16.6, Cell death regulatory protein GRIM-19, NADH-ubiquinone oxidoreductase B16.6 subunit, GRIM-19, Complex I-B16.6, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, GRIM19, NDUFA13 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9P0J0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (NDUFA13) is a ~16 kDa protein. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. 1. Stroud, DA. et al. (2016) Nature 538, 123-126. PMID: 27626371 2. Barnich, N. et al. (2005) The Journal of biological chemistry 280, 19021-6. PMID: 15753091 | ||||||||
| Nota | For research use only. |


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