

| Número de catálogo | HP702014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human NEK1 Polyclonal Antibody (HP702014) is a rabbit polyclonal antibody detecting Serine/threonine-protein kinase Nek1; 2.7.11.1; Never in mitosis A-related kinase 1; NimA-related protein kinase 1; Renal carcinoma antigen NY-REN-55; NEK1; KIAA1901. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human NEK1 (Cys1177-Glu1258). | ||||||||
| Objetivo | Serine/threonine-protein kinase Nek1; 2.7.11.1; Never in mitosis A-related kinase 1; NimA-related protein kinase 1; Renal carcinoma antigen NY-REN-55; NEK1; KIAA1901 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q96PY6 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Serine/threonine-protein kinase Nek1 is a ~142 kDa protein. Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. May be implicated in the control of meiosis. Involved in cilium assembly. 1. Chen, Y. et al. (2010) Biochemical and biophysical research communications 394, 798-803. PMID: 20230784 2. Thiel, C. et al. (2011) American journal of human genetics 88, 106-14. PMID: 21211617 | ||||||||
| Nota | For research use only |

Lane 1: Mouse brain lysate
Lane 2: Mouse testis lysate
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