

| Numéro de catalogue | HF982014 | ||||||||
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| Description |
Anti-Human NFATC1 Polyclonal Antibody (HF982014) is a rabbit polyclonal antibody detecting NFATc1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NFATC1 (Ser423-Ile700). | ||||||||
| Cible | Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O95644 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) is a ~101 kDa protein. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function. 1. Chuvpilo, S. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 162, 7294-301. PMID: 10358178 | ||||||||
| Note | For research use only. |
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