

| Numéro de catalogue | HF966014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human NIPSNAP2 Polyclonal Antibody (HF966014) is a rabbit polyclonal antibody detecting NipSnap2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NIPSNAP2 (Ala60-Gln286). | ||||||||
| Cible | Protein NipSnap homolog 2, NipSnap2, Glioblastoma-amplified sequence, NIPSNAP2, GBAS | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O75323 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Protein NipSnap homolog 2 (NIPSNAP2) is a ~33 kDa protein. Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2). 1. Princely Abudu, Y. et al. (2019) Developmental cell 49, 509-525.e12. PMID: 30982665 | ||||||||
| Note | For research use only. |
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