Anti-Human NMES1 Recombinant Antibody (SAA1899) (HA194013)

Name: Anti-Human NMES1 Recombinant Antibody (SAA1899)
Brand: abinScience
SKU: HA194013
Price: 196 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA194013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1899

Cible

Protein FOAP-11, C15orf48, NMES1, Normal mucosa of esophagus-specific gene 1 protein

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9C002

RRID

Anti-Human NMES1 Antibody (SAA1899) (abinScience Cat# HA194013, RRID:AB_3727663)
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Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Cytochrome c oxidase associated subunit FA4L3 (NMES1) is a ~9 kDa protein. Mitochondrial small peptide that orchestrates a two-pronged immunoregulatory mechanism in response to inflammatory stimuli. Replaces the canonical cytochrome c oxidase subunit COXFA4 in mitochondrial complex IV and targets it to degradation, attenuating mitochondrial respiration, reducing membrane potential as well as ROS generation and modulates innate immune signaling. Additionally, initiates stress-independent autophagy by lowering ATP levels, activating AMPK-ULK1 signaling, boosting glutathione production, and thereby mitigating oxidative stress and supporting immune tolerance.

1. Lee, CQE. et al. (2021) Nature communications 12, 2130. PMID: 33837217

2. Clayton, SA. et al. (2021) Science advances 7, eabl5182. PMID: 34878835

3. Takakura, Y. et al. (2024) Nature communications 15, 953. PMID: 38296961

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human NMES1 Antibody (SAA1899)

Reférences

Fiche technique

Anti-Human NMES1 Recombinant Antibody (SAA1899).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai