Anti-Human NMT1 Polyclonal Antibody (HB608014)

Name: Anti-Human NMT1 Polyclonal Antibody
Brand: abinScience
SKU: HB608014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HB608014

説明

Anti-Human NMT1 Polyclonal Antibody (HB608014) is a rabbit polyclonal antibody detecting NMT1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human NMT1 (Thr108-Gln496).

ターゲット

Myristoyl-CoA:protein N-myristoyltransferase 1, Type I N-myristoyltransferase, NMT 1, Peptide N-myristoyltransferase 1, NMT1, Glycylpeptide N-tetradecanoyltransferase 1, NMT

精製

Purified by antigen affinity column.

アクセッション番号

P30419

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) is a ~56 kDa protein. Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle.

1. Montgomery, C. et al. (2012) The Journal of biological chemistry 287, 33227-36. PMID: 22865860

2. Thinon, E. et al. (2014) Nature communications 5, 4919. PMID: 25255805

3. Chen, YC. et al. (2020) Scientific reports 10, 11952. PMID: 32686708

4. Sun, Y. et al. (2022) Cancer letters 529, 126-138. PMID: 34999170

5. Glover, CJ. et al. (1997) The Journal of biological chemistry 272, 28680-9. PMID: 9353336

6. Giang, DK. et al. (1998) The Journal of biological chemistry 273, 6595-8. PMID: 9506952

7. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017

8. Dian, C. et al. (2020) Nature communications 11, 1132. PMID: 32111831

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human NMT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human NMT1 Polyclonal Antibody (HB608014)

概要

イメージ

参考文献

データシート

SDS