Anti-Human NPHP4 Polyclonal Antibody (HF918014)

Name: Anti-Human NPHP4 Polyclonal Antibody
Brand: abinScience
SKU: HF918014
Price: 168 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF918014

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human NPHP4 (His1171-Gln1426).

Objetivo

KIAA0673, Nephrocystin-4, NPHP4, Nephroretinin

Purificación

Purified by antigen affinity column.

Número de acceso

O75161

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Nephrocystin-4 (NPHP4) is a ~157 kDa protein. Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis. Required for building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Seems to recruit INT to basal bodies of motile cilia which subsequently interacts with actin-modifying proteins such as DAAM1.

1. Delous, M. et al. (2009) Human molecular genetics 18, 4711-23. PMID: 19755384

2. Sang, L. et al. (2011) Cell 145, 513-28. PMID: 21565611

3. Burcklé, C. et al. (2011) Human molecular genetics 20, 2611-27. PMID: 21498478

4. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112

5. Habbig, S. et al. (2011) The Journal of cell biology 193, 633-42. PMID: 21555462

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human NPHP4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo