Anti-Human NPHP4 Polyclonal Antibody (HF918014)

Name: Anti-Human NPHP4 Polyclonal Antibody
Brand: abinScience
SKU: HF918014
Price: 168 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug

Nombre :

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF918014

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human NPHP4 (His1171-Gln1426).

Cible

KIAA0673, Nephrocystin-4, NPHP4, Nephroretinin

Purification

Purified by antigen affinity column.

Numéro d'accès

O75161

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Nephrocystin-4 (NPHP4) is a ~157 kDa protein. Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis. Required for building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Seems to recruit INT to basal bodies of motile cilia which subsequently interacts with actin-modifying proteins such as DAAM1.

1. Delous, M. et al. (2009) Human molecular genetics 18, 4711-23. PMID: 19755384

2. Sang, L. et al. (2011) Cell 145, 513-28. PMID: 21565611

3. Burcklé, C. et al. (2011) Human molecular genetics 20, 2611-27. PMID: 21498478

4. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112

5. Habbig, S. et al. (2011) The Journal of cell biology 193, 633-42. PMID: 21555462

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human NPHP4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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