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Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818) (HB010013)

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Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)
Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)
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  • 1mg
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Vista general
Número de catálogoHB010013
Descripción
Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818) (HB010013) is a human monoclonal antibody detecting NPR1/NPR-A in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG4, kappa
ID de clonSAA1818
Objetivo ANP-A, Atrial natriuretic peptide receptor type A, Guanylate cyclase A, NPR1, NPR-A, ANPRA, GC-A, ANPR-A, Atrial natriuretic peptide receptor 1
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P16066
RRID

Anti-Human NPR1/NPR-A Antibody (SAA1818) (abinScience Cat# HB010013, RRID:AB_3727580)
_x005F_x000D_

Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Atrial natriuretic peptide receptor 1 (NPR1/NPR-A) is a ~118 kDa protein. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.

1. Liu, S. et al. (2025) Nature structural & molecular biology 32, 469-478. PMID: 39543315
2. Long, C. et al. (2022) Aging cell 21, e13699. PMID: 36016499
Nota For research use only.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Imágenes
  • Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)

    SDS-PAGE

    SDS-PAGE for Anti-Human NPR1/NPR-A Antibody (SAA1818).

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)

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