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Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818) (HB010013)

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Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)
Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)
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Aperçu
Numéro de catalogueHB010013
Description
Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818) (HB010013) is a human monoclonal antibody detecting NPR1/NPR-A in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4, kappa
ID de cloneSAA1818
Cible ANP-A, Atrial natriuretic peptide receptor type A, Guanylate cyclase A, NPR1, NPR-A, ANPRA, GC-A, ANPR-A, Atrial natriuretic peptide receptor 1
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P16066
RRID

Anti-Human NPR1/NPR-A Antibody (SAA1818) (abinScience Cat# HB010013, RRID:AB_3727580)
_x005F_x000D_

Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Atrial natriuretic peptide receptor 1 (NPR1/NPR-A) is a ~118 kDa protein. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Plays an essential role in the regulation of endothelial cell senescence and vascular aging. Upon activation by ANP or BNP, stimulates the production of cyclic guanosine monophosphate (cGMP) that promotes vascular tone and volume homeostasis by activation of protein kinase cGMP-dependent 1/PRKG1 and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis.

1. Liu, S. et al. (2025) Nature structural & molecular biology 32, 469-478. PMID: 39543315
2. Long, C. et al. (2022) Aging cell 21, e13699. PMID: 36016499
Note For research use only.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
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  • Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)

    SDS-PAGE

    SDS-PAGE for Anti-Human NPR1/NPR-A Antibody (SAA1818).

Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Volume
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human NPR1/NPR-A Recombinant Antibody (SAA1818)

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