Anti-Human NR0B2 Polyclonal Antibody (HS713014)

Name: Anti-Human NR0B2 Polyclonal Antibody
Brand: abinScience
SKU: HS713014
Price: 96 USD
Availability: InStock

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Обзор

Каталожный номер

HS713014

Описание

Anti-Human NR0B2 Polyclonal Antibody (HS713014) is a rabbit polyclonal antibody detecting NR0B2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human NR0B2 (Met1-Arg257).

Цель

NR0B2

Очистка

Purified by antigen affinity column.

Номер доступа

Q15466

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

Nuclear receptor subfamily 0 group B member 2, Orphan nuclear receptor SHP, Small heterodimer partner, NR0B2, SHP

Фон

Nuclear receptor subfamily 0 group B member 2 (NR0B2) is a ~28 kDa protein. Transcriptional regulator that acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with which it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1. Essential component of the liver circadian clock which via its interaction with NR1D1 and RORG regulates NPAS2-mediated hepatic lipid metabolism. Regulates the circadian expression of cytochrome P450 (CYP) enzymes.

1. Musille, PM. et al. (2012) Nature structural & molecular biology 19, 532-S2. PMID: 22504882

2. Kim, JY. et al. (2004) Molecular endocrinology (Baltimore, Md.) 18, 776-90. PMID: 14752053

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-NR0B2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate

Ссылки

Даташит

Anti-Human NR0B2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human NR0B2 Polyclonal Antibody (HS713014)

Обзор

Изображения

Ссылки

Даташит

SDS