Anti-Human NR1D1 Polyclonal Antibody (HB802014)

Name: Anti-Human NR1D1 Polyclonal Antibody
Brand: abinScience
SKU: HB802014
Price: 96 USD
Availability: InStock

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Каталожный номер

HB802014

Описание

Anti-Human NR1D1 Polyclonal Antibody (HB802014) is a rabbit polyclonal antibody detecting NR1D1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human NR1D1 (Thr431-Gln614).

Цель

THRAL, EAR1, EAR-1, NR1D1, Rev-erbA-alpha, Nuclear receptor subfamily 1 group D member 1, HREV, V-erbA-related protein 1

Очистка

Purified by antigen affinity column.

Номер доступа

P20393

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Nuclear receptor subfamily 1 group D member 1 (NR1D1) is a ~66 kDa protein. Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target genes and can bind to DNA as either monomers or homodimers, depending on the nature of the response element.

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-NR1D1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: Mouse skeletal muscle lysate
Lane 2: Rat lung lysate
Lane 3: Rat liver lysate
Lane 4: Rat skeletal muscle lysate

Ссылки

Даташит

Anti-Human NR1D1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human NR1D1 Polyclonal Antibody (HB802014)

Обзор

Изображения

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