

| Numéro de catalogue | HA413014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human NR2E1 Polyclonal Antibody (HA413014) is a rabbit polyclonal antibody detecting NR2E1 in WB, IHC, ELISA. Suitable for Human, Mouse, and Chicken.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | WB, IHC, ELISA | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NR2E1 (Met175-Ile385). | ||||||||
| Cible | NR2E1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Y466 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Noms alternatifs | Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1 | ||||||||
| Contexte | Nuclear receptor subfamily 2 group E member 1 (NR2E1) is a ~42 kDa protein. Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells. | ||||||||
| Note | For research use only. |
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