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| カタログ番号 | HA413014 | ||||||||
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| 説明 |
Anti-Human NR2E1 Polyclonal Antibody (HA413014) is a rabbit polyclonal antibody detecting NR2E1 in WB, IHC, ELISA. Suitable for Human, Mouse, and Chicken.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | WB, IHC, ELISA | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NR2E1 (Met175-Ile385). | ||||||||
| ターゲット | NR2E1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9Y466 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1 | ||||||||
| 背景 | Nuclear receptor subfamily 2 group E member 1 (NR2E1) is a ~42 kDa protein. Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells. | ||||||||
| 注意事項 | For research use only. |
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