

| Numéro de catalogue | HP177014 | ||||||||
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NRCAM (Thr47-Ala451). | ||||||||
| Cible | Ng-CAM-related, KIAA0343, hBravo, NRCAM, NgCAM-related cell adhesion molecule, Neuronal cell adhesion molecule, Neuronal surface protein Bravo, Nr-CAM | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q92823 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Neuronal cell adhesion molecule (NRCAM) is a ~143 kDa protein. Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-NRCAM polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse cerebellum lysate
Lane 3: Rat brain lysate
Lane 4: Rat cerebellum lysate
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