

| Numéro de catalogue | HP203014 | ||||||||
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| Description |
Anti-Human NSUN5 Polyclonal Antibody (HP203014) is a rabbit polyclonal antibody detecting NSUN5 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NSUN5 (Met1-Arg429). | ||||||||
| Cible | NOL1R, NOL1-related protein, NSUN5, 28S rRNA (cytosine-C(5))-methyltransferase, WBSCR20A, NOL1/NOP2/Sun domain family member 5, WBSCR20, NSUN5A, Williams-Beuren syndrome chromosomal region 20A protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q96P11 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | 28S rRNA (cytosine-C(5))-methyltransferase (NSUN5) is a ~46 kDa protein. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA. m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity. Required for corpus callosum and cerebral cortex development. 1. Sharma, S. et al. (2013) Nucleic acids research 41, 9062-76. PMID: 23913415 2. Janin, M. et al. (2019) Acta neuropathologica 138, 1053-1074. PMID: 31428936 3. Heissenberger, C. et al. (2019) Nucleic acids research 47, 11807-11825. PMID: 31722427 | ||||||||
| Note | For research use only. |
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