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| カタログ番号 | HA244013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1874 | ||||
| ターゲット | NTAN1, PNAA, Protein N-terminal asparagine amidohydrolase, Protein NH2-terminal asparagine deamidase, Protein NTN-amidase, Protein N-terminal Asn amidase, Protein N-terminal asparagine amidase, PNAD, Protein NH2-terminal asparagine amidohydrolase | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q96AB6 | ||||
| RRID | Anti-Human NTAN1/PNAd Antibody (SAA1874) (abinScience Cat# HA244013, RRID:AB_3727637) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Protein N-terminal asparagine amidohydrolase (NTAN1/PNAd) is a ~34 kDa protein. N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn. | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human NTAN1/PNAd Antibody (SAA1874)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
