Anti-Human NUDT3 Polyclonal Antibody (HF767014)

Name: Anti-Human NUDT3 Polyclonal Antibody
Brand: abinScience
SKU: HF767014
Price: 96 USD
Availability: InStock

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Каталожный номер

HF767014

Описание

Anti-Human NUDT3 Polyclonal Antibody (HF767014) is a rabbit polyclonal antibody detecting NUDT3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human NUDT3 (Gly16-Ser163).

Цель

Diphosphoinositol polyphosphate phosphohydrolase 1, DIPP-1, 3.6.1.52, Diadenosine hexaphosphate hydrolase, Ap6A hydrolase, 3.6.1.61, Endopolyphosphatase, 3.6.1.10, Nucleoside diphosphate-linked moiety X motif 3, Nudix motif 3, m7GpppN-mRNA hydrolase, 3.6.1.62, m7GpppX diphosphatase, 3.6.1.59, NUDT3, DIPP, DIPP1

Очистка

Purified by antigen affinity column.

Номер доступа

O95989

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Diphosphoinositol polyphosphate phosphohydrolase 1 (NUDT3) is a ~19 kDa protein. Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphosphate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) and diadenosine 5',5'''- P1,P5-pentaphosphate (Ap5A) being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A.

1. Yang, X. et al. (1999) The Journal of biological chemistry 274, 35434-40. PMID: 10585413

2. Fisher, DI. et al. (2002) The Journal of biological chemistry 277, 47313-7. PMID: 12370170

3. Safrany, ST. et al. (1998) The EMBO journal 17, 6599-607. PMID: 9822604

4. Safrany, ST. et al. (1999) The Journal of biological chemistry 274, 21735-40. PMID: 10419486

5. Grudzien-Nogalska, E. et al. (2016) RNA (New York, N.Y.) 22, 773-81. PMID: 26932476

6. Sahu, S. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 19245-19253. PMID: 32727897

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human NUDT3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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Anti-Human NUDT3 Polyclonal Antibody (HF767014)

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