

| Número de catálogo | HP845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human OSBPL2 (Ala96-Asp325). | ||||||||
| Objetivo | ORP-2, Oxysterol-binding protein-related protein 2, ORP2, OSBPL2, KIAA0772, OSBP-related protein 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9H1P3 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||||
| Información de uso del producto |
| ||||||||
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Oxysterol-binding protein-related protein 2 (OSBPL2) is a ~55 kDa protein. Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro). 1. Wang, H. et al. (2019) Molecular cell 73, 458-473.e7. PMID: 30581148 2. Xu, Y. et al. (2001) The Journal of biological chemistry 276, 18407-14. PMID: 11279184 3. Suchanek, M. et al. (2007) The Biochemical journal 405, 473-80. PMID: 17428193 4. Hynynen, R. et al. (2009) Journal of lipid research 50, 1305-15. PMID: 19224871 | ||||||||
| Nota | For research use only. |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский