

| Número de catálogo | HP943107 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FCM |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG2a, kappa |
| ID de clon | SAA0867 |
| Objetivo | Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | Q99571 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Fondo | P2X purinoceptor 4 (P2RX4) is a ~43 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4. Activated by extracellularly released ATP, it plays multiple role in immunity and central nervous system physiology. Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation. Also participates in basal T-cell activity without TCR/CD3 stimulation. 1. Garcia-Guzman, M. et al. (1997) Molecular pharmacology 51, 109-18. PMID: 9016352 2. Hamoudi, C. et al. (2022) Journal of immunology (Baltimore, Md. : 1950) 208, 1115-1127. PMID: 35165166 |
| Nota | For research use only. |

SDS-PAGE for Anti-Human P2RX4 Antibody (SAA0867)




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