

| Número de catálogo | HP943147 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FCM |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG2a, kappa |
| ID de clon | SAA0867 |
| Conjugación | PerCP |
| Objetivo | Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Productos asociados | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PerCP |
| Número de acceso | Q99571 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Fondo | P2X purinoceptor 4 (P2RX4) is a ~43 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4. Activated by extracellularly released ATP, it plays multiple role in immunity and central nervous system physiology. Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation. Also participates in basal T-cell activity without TCR/CD3 stimulation. 1. Garcia-Guzman, M. et al. (1997) Molecular pharmacology 51, 109-18. PMID: 9016352 2. Hamoudi, C. et al. (2022) Journal of immunology (Baltimore, Md. : 1950) 208, 1115-1127. PMID: 35165166 |
| Nota | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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