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| カタログ番号 | HT117014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human P2RX6 Polyclonal Antibody (HT117014) is a rabbit polyclonal antibody detecting P2RX6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human P2RX6 (Lys61-Gly333). | ||||||||
| ターゲット | Purinergic receptor, P2XM, Purinergic receptor P2X-like 1, P2RXL1, P2X purinoceptor 6, P2X6, ATP receptor, P2RX6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O15547 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | P2X purinoceptor 6 (P2RX6) is a ~48 kDa protein. May act as a modulatory subunit rather than a functional channel. Unlike other P2XRs members, P2RX6 does not seem to form functional homotrimers. P2RX6 requires the presence of P2RX4 or P2RX2 to shuttle it to the plasma membrane where it may form functional heterotrimeric receptors at the plasma membrane. P2RX6 can be translocated to the nucleus and functions as a nuclear regulator of post-transcriptional modifications in neurons. 1. Hausmann, R. et al. (2012) The Journal of biological chemistry 287, 13930-43. PMID: 22378790 | ||||||||
| 注意事項 | For research use only. |
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