

| Numéro de catalogue | HA344014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PACS2 Polyclonal Antibody (HA344014) is a rabbit polyclonal antibody detecting PACS2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PACS2 (Met22-His181). | ||||||||
| Cible | Phosphofurin acidic cluster sorting protein 2, PACS-2, PACS1-like protein, PACS2, KIAA0602, PACS1L | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q86VP3 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Phosphofurin acidic cluster sorting protein 2 (PACS2) is a ~97 kDa protein. Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PACS2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
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