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| カタログ番号 | HA344014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human PACS2 Polyclonal Antibody (HA344014) is a rabbit polyclonal antibody detecting PACS2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PACS2 (Met22-His181). | ||||||||
| ターゲット | Phosphofurin acidic cluster sorting protein 2, PACS-2, PACS1-like protein, PACS2, KIAA0602, PACS1L | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q86VP3 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Phosphofurin acidic cluster sorting protein 2 (PACS2) is a ~97 kDa protein. Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-PACS2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
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