

| Каталожный номер | HB365014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human PADI6 Polyclonal Antibody (HB365014) is a rabbit polyclonal antibody detecting Protein-arginine deiminase type-6; 3.5.3.15; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI; PADI6; PAD6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human PADI6 (Val2-Pro694). | ||||||||
| Цель | Protein-arginine deiminase type-6; 3.5.3.15; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI; PADI6; PAD6 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q6TGC4 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Inactive protein-arginine deiminase type-6 (PADI6) is a ~77 kDa protein. Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development. Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos. They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins and proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation. In contrast to other members of the family, does not show protein-arginine deiminase activity due to its inability to bind Ca(2+). 1. Jentoft, IMA. et al. (2023) Cell 186, 5308-5327.e25. PMID: 37922900 2. Ranaivoson, FM. et al. (2024) IUCrJ 11, 395-404. PMID: 38656308 3. Williams, JPC. et al. (2024) Computational and structural biotechnology journal 23, 3258-3269. PMID: 39286527 | ||||||||
| Примечание | For research use only |
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