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Anti-Human pan-Frizzled Recombinant Antibody (F6) (HV162307)

Anti-Human pan-Frizzled Recombinant Antibody (F6)
Anti-Human pan-Frizzled Recombinant Antibody (F6)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Vista general

  • Imágenes

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  • Datasheet

  • SDS

Vista general
Número de catálogoHV162307
Reactividad de especiesHuman
AplicacionesELISA, FCM, IF, SPR
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonF6
Objetivo FzE1, Frizzled-1, hFz1, Fz-1, FZD1, Frizzled-2, FzE2, Fz-2, hFz2, FZD2, Frizzled-5, FzE5, C2orf31, hFz5, FZD5, Fz-5, Frizzled-7, hFz7, FzE3, Fz-7, FZD7, hFz8, Frizzled-8, Fz-8, FZD8
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9UP38, Q14332, Q13467, O75084, Q9H461
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Frizzled-1 (FZD1) is a ~71 kDa protein. Receptor for Wnt proteins. Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B. Contradictory results showing activation by WNT7B have been described for mouse. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.

1. Gazit, A. et al. (1999) Oncogene 18, 5959-66. PMID: 10557084
Nota For research use only.
Imágenes
  • Anti-Human pan-Frizzled Recombinant Antibody (F6)

    SDS-PAGE

    SDS-PAGE for Anti-Human pan-FZD Antibody (F6)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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