Anti-Human papillomavirus type 16 E6/Protein E6 Recombinant Nanobody (SAA1338) (VK451023)

Name: Anti-Human papillomavirus type 16 E6/Protein E6 Recombinant Nanobody (SAA1338)
Brand: abinScience
SKU: VK451023
Price: 126 USD
Availability: InStock

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20ug
50ug
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1mg

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Datasheet
SDS

Vista general

Número de catálogo

VK451023

Descripción

Anti-Human papillomavirus type 16 E6/Protein E6 Nanobody (SAA1338) [SAA1338] (VK451023) is a alpaca monoclonal antibody detecting Protein E6 in ELISA, IF, WB.

Highlights

●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human papillomavirus 16 (HPV16)

Aplicaciones

ELISA, IF, WB

Especie huésped

Alpaca

Clonalidad

Monoclonal

Isotipo

VHH-8His-Cys-tag

ID de clon

SAA1338

Objetivo

Protein E6, E6

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column.

Número de acceso

P03126

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Protein E6 is a ~19 kDa protein. Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).

Nota

For research use only.

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