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Anti-Human papillomavirus type 16 E6/Protein E6 Recombinant Nanobody (SAA1338) (VK451023)

Anti-Human papillomavirus type 16 E6/Protein E6 Recombinant Nanobody (SAA1338)
Anti-Human papillomavirus type 16 E6/Protein E6 Recombinant Nanobody (SAA1338)
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Спецификация:
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Обзор
Каталожный номерVK451023
Описание
Anti-Human papillomavirus type 16 E6/Protein E6 Nanobody (SAA1338) [SAA1338] (VK451023) is a alpaca monoclonal antibody detecting Protein E6 in ELISA, IF, WB.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman papillomavirus 16 (HPV16)
ПримененияELISA, IF, WB
Хозяинский видAlpaca
КлоональностьMonoclonal
ИзотипVHH-8His-Cys-tag
ID клонаSAA1338
Цель Protein E6, E6
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Purified by Nickel column.
Номер доступа P03126
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Protein E6 is a ~19 kDa protein. Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).

Примечание For research use only.
Изображения
  • Anti-Human papillomavirus type 16 E6/Protein E6 Recombinant Nanobody (SAA1338)

    SDS-PAGE

    SDS-PAGE for Anti-Human papillomavirus type 16 E6/Protein E6 Nanobody (SAA1338)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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