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Anti-Human PARD3 Polyclonal Antibody (HC188014)

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Vista general
Número de catálogoHC188014
Descripción
Anti-Human PARD3 Polyclonal Antibody (HC188014) is a rabbit polyclonal antibody detecting PARD3. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PARD3 (Met1-Glu81&Thr583-Arg683).
Objetivo ASIP, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR-3, PAR3, PAR3-alpha, PAR3A, PARD-3, PARD3, Partitioning defective 3 homolog
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q8TEW0
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Partitioning defective 3 homolog (PARD3) is a ~151 kDa protein. Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly.

1. Johansson, A. et al. (2000) Journal of cell science 113 ( Pt 18), 3267-75. PMID: 10954424
2. Chen, X. et al. (2017) Human mutation 38, 378-389. PMID: 27925688
3. Joberty, G. et al. (2000) Nature cell biology 2, 531-9. PMID: 10934474
4. Khazaei, MR. et al. (2009) The Journal of biological chemistry 284, 33571-9. PMID: 19812038
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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