Anti-Human PARP14 IP Recombinant Antibody (SAA0213) (HS727013)

Name: Anti-Human PARP14 IP Recombinant Antibody (SAA0213)
Brand: abinScience
SKU: HS727013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HS727013

Reactividad de especies

Human

Aplicaciones

ELISA, IF, IP

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG1

ID de clon

SAA0213

Objetivo

BAL2, B aggressive lymphoma protein 2, PARP14, Poly [ADP-ribose] polymerase 14, Protein mono-ADP-ribosyltransferase PARP14, PARP-14, ADP-ribosyltransferase diphtheria toxin-like 8, KIAA1268, ARTD8

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q460N5

RRID

Anti-Human PARP14 IP Antibody (SAA0213) (abinScience Cat# HS727013, RRID:AB_3729747)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Protein mono-ADP-ribosyltransferase PARP14 is a ~202 kDa protein. ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation. Has been shown to catalyze the mono-ADP-ribosylation of STAT1 at 'Glu-657' and 'Glu-705', thus decreasing STAT1 phosphorylation which negatively regulates pro-inflammatory cytokine production in macrophages in response to IFNG stimulation. However, the role of ADP-ribosylation in the prevention of STAT1 phosphorylation has been called into question and it has been suggested that the inhibition of phosphorylation may be the result of sumoylation of STAT1 'Lys-703'. Mono-ADP-ribosylates STAT6; enhancing STAT6-dependent transcription.

1. Aguiar, RC. et al. (2005) The Journal of biological chemistry 280, 33756-65. PMID: 16061477

2. Kleine, H. et al. (2008) Molecular cell 32, 57-69. PMID: 18851833

3. Vyas, S. et al. (2014) Nature communications 5, 4426. PMID: 25043379

4. Iwata, H. et al. (2016) Nature communications 7, 12849. PMID: 27796300

5. Begitt, A. et al. (2018) Nature communications 9, 2144. PMID: 29858569

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human PARP14 IP Antibody (SAA0213)

Referencias

Datasheet

Anti-Human PARP14 IP Recombinant Antibody (SAA0213).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo