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Anti-Human PCBP2 Polyclonal Antibody (HS896014)

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Vista general
Número de catálogoHS896014
Descripción
Anti-Human PCBP2 Polyclonal Antibody (HS896014) is a rabbit polyclonal antibody detecting PCBP2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human PCBP2 (Asn11-Ser173).
Objetivo Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2
Purificación Purified by antigen affinity column.
Número de acceso Q15366
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Poly(rC)-binding protein 2 (PCBP2) is a ~38 kDa protein. Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Also binds poly(rU). Acts as a negative regulator of antiviral signaling. Negatively regulates cellular antiviral responses mediated by MAVS signaling.

1. Walter, BL. et al. (2002) Journal of virology 76, 12008-22. PMID: 12414943
2. Leffers, H. et al. (1995) European journal of biochemistry 230, 447-53. PMID: 7607214
3. You, F. et al. (2009) Nature immunology 10, 1300-8. PMID: 19881509
4. Gu, H. et al. (2022) Nature communications 13, 1564. PMID: 35322803
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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