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| カタログ番号 | HS896014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human PCBP2 Polyclonal Antibody (HS896014) is a rabbit polyclonal antibody detecting PCBP2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PCBP2 (Asn11-Ser173). | ||||||||
| ターゲット | Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q15366 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Poly(rC)-binding protein 2 (PCBP2) is a ~38 kDa protein. Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Also binds poly(rU). Acts as a negative regulator of antiviral signaling. Negatively regulates cellular antiviral responses mediated by MAVS signaling. 1. Walter, BL. et al. (2002) Journal of virology 76, 12008-22. PMID: 12414943 2. Leffers, H. et al. (1995) European journal of biochemistry 230, 447-53. PMID: 7607214 3. You, F. et al. (2009) Nature immunology 10, 1300-8. PMID: 19881509 4. Gu, H. et al. (2022) Nature communications 13, 1564. PMID: 35322803 | ||||||||
| 注意事項 | For research use only. |
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